brl37344 sodium salt Search Results


brl37344 sodium salt  (Tocris)
92
Tocris brl37344 sodium salt
β 2 -AR agonists exert proneurogenic effects on ahNPCs. (A) Representative confocal images of MAP-2 (red) and nestin (green) immunolabeling in ahNPCs after 24 h treatment with vehicle (left panel) and 10 nM salmeterol (right panel). Nuclei were stained with DAPI (blue). MAP-2 + /nestin − cells are indicated (arrowheads). Magnification 400X, scale bar = 20 µm. (B-C) Effects of β 2 -AR agonists salmeterol (0.1–10 nM) (B) and formoterol (0.01–10 nM) (C) on neuronal differentiation of ahNPCs. (D-E) Effects of 24-h treatment with salmeterol (SAL) and formoterol (FORM) on GFAP + (D) and NG-2 + (E) cells. (F) Effect of 3 nM SAL in presence of vehicle, ICI118551, SR59230A, or CGP20712 antagonists. (G) Effects of 1 µM NE, 10 nM SAL, 10 nM FORM, and 100 nM <t>BRL37344</t> (BRL) on neuronal differentiation of ahNPCs derived from β 2 -AR knockout mice. (H) Effects of salmeterol (0.0001–1 µM) on ahNPC proliferation. Fold change compared to vehicle-treated (−) ahNPCs. All experiments (n = 3) were run in triplicates. Data are expressed as mean ± S.D. ** p < 0.01, *** p < 0.001 vs. vehicle-treated cells; ### p < 0.001 vs. 3-nM SAL-treated cells (one-way ANOVA, Tukey’s post hoc analysis).
Brl37344 Sodium Salt, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/brl37344+sodium+salt/pmc06751403-37-25-30?v=Tocris
Average 92 stars, based on 1 article reviews
brl37344 sodium salt - by Bioz Stars, 2026-08
92/100 stars
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brl 37344 sodium salt hydrate  (Tocris)
93
Tocris brl 37344 sodium salt hydrate
β 2 -AR agonists exert proneurogenic effects on ahNPCs. (A) Representative confocal images of MAP-2 (red) and nestin (green) immunolabeling in ahNPCs after 24 h treatment with vehicle (left panel) and 10 nM salmeterol (right panel). Nuclei were stained with DAPI (blue). MAP-2 + /nestin − cells are indicated (arrowheads). Magnification 400X, scale bar = 20 µm. (B-C) Effects of β 2 -AR agonists salmeterol (0.1–10 nM) (B) and formoterol (0.01–10 nM) (C) on neuronal differentiation of ahNPCs. (D-E) Effects of 24-h treatment with salmeterol (SAL) and formoterol (FORM) on GFAP + (D) and NG-2 + (E) cells. (F) Effect of 3 nM SAL in presence of vehicle, ICI118551, SR59230A, or CGP20712 antagonists. (G) Effects of 1 µM NE, 10 nM SAL, 10 nM FORM, and 100 nM <t>BRL37344</t> (BRL) on neuronal differentiation of ahNPCs derived from β 2 -AR knockout mice. (H) Effects of salmeterol (0.0001–1 µM) on ahNPC proliferation. Fold change compared to vehicle-treated (−) ahNPCs. All experiments (n = 3) were run in triplicates. Data are expressed as mean ± S.D. ** p < 0.01, *** p < 0.001 vs. vehicle-treated cells; ### p < 0.001 vs. 3-nM SAL-treated cells (one-way ANOVA, Tukey’s post hoc analysis).
Brl 37344 Sodium Salt Hydrate, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/brl37344+sodium+salt/pm38378892-217-28-62?v=Tocris
Average 93 stars, based on 1 article reviews
brl 37344 sodium salt hydrate - by Bioz Stars, 2026-08
93/100 stars
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brl 37344, sodium salt  (Aladdin Scientific Corporation)
N/A
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brl 37344 sodium salt hydrate  (Biosynth Carbosynth)
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Image Search Results


β 2 -AR agonists exert proneurogenic effects on ahNPCs. (A) Representative confocal images of MAP-2 (red) and nestin (green) immunolabeling in ahNPCs after 24 h treatment with vehicle (left panel) and 10 nM salmeterol (right panel). Nuclei were stained with DAPI (blue). MAP-2 + /nestin − cells are indicated (arrowheads). Magnification 400X, scale bar = 20 µm. (B-C) Effects of β 2 -AR agonists salmeterol (0.1–10 nM) (B) and formoterol (0.01–10 nM) (C) on neuronal differentiation of ahNPCs. (D-E) Effects of 24-h treatment with salmeterol (SAL) and formoterol (FORM) on GFAP + (D) and NG-2 + (E) cells. (F) Effect of 3 nM SAL in presence of vehicle, ICI118551, SR59230A, or CGP20712 antagonists. (G) Effects of 1 µM NE, 10 nM SAL, 10 nM FORM, and 100 nM BRL37344 (BRL) on neuronal differentiation of ahNPCs derived from β 2 -AR knockout mice. (H) Effects of salmeterol (0.0001–1 µM) on ahNPC proliferation. Fold change compared to vehicle-treated (−) ahNPCs. All experiments (n = 3) were run in triplicates. Data are expressed as mean ± S.D. ** p < 0.01, *** p < 0.001 vs. vehicle-treated cells; ### p < 0.001 vs. 3-nM SAL-treated cells (one-way ANOVA, Tukey’s post hoc analysis).

Journal: Frontiers in Pharmacology

Article Title: Salmeterol, a β2 Adrenergic Agonist, Promotes Adult Hippocampal Neurogenesis in a Region-Specific Manner

doi: 10.3389/fphar.2019.01000

Figure Lengend Snippet: β 2 -AR agonists exert proneurogenic effects on ahNPCs. (A) Representative confocal images of MAP-2 (red) and nestin (green) immunolabeling in ahNPCs after 24 h treatment with vehicle (left panel) and 10 nM salmeterol (right panel). Nuclei were stained with DAPI (blue). MAP-2 + /nestin − cells are indicated (arrowheads). Magnification 400X, scale bar = 20 µm. (B-C) Effects of β 2 -AR agonists salmeterol (0.1–10 nM) (B) and formoterol (0.01–10 nM) (C) on neuronal differentiation of ahNPCs. (D-E) Effects of 24-h treatment with salmeterol (SAL) and formoterol (FORM) on GFAP + (D) and NG-2 + (E) cells. (F) Effect of 3 nM SAL in presence of vehicle, ICI118551, SR59230A, or CGP20712 antagonists. (G) Effects of 1 µM NE, 10 nM SAL, 10 nM FORM, and 100 nM BRL37344 (BRL) on neuronal differentiation of ahNPCs derived from β 2 -AR knockout mice. (H) Effects of salmeterol (0.0001–1 µM) on ahNPC proliferation. Fold change compared to vehicle-treated (−) ahNPCs. All experiments (n = 3) were run in triplicates. Data are expressed as mean ± S.D. ** p < 0.01, *** p < 0.001 vs. vehicle-treated cells; ### p < 0.001 vs. 3-nM SAL-treated cells (one-way ANOVA, Tukey’s post hoc analysis).

Article Snippet: The following drugs were utilized: L-(-)-norepinephrine-(+)-bitartrate salt monohydrate (NE) purchased from Sigma–Aldrich (Milan, Italy), salmeterol xinafoate, formoterol hemifumarate, ICI118,551 hydrochloride, CGP20712 dihydrochloride, SR59230A hydrochloride, and BRL37344 sodium salt purchased from Tocris (Bioscience, Bristol, UK).

Techniques: Immunolabeling, Staining, Derivative Assay, Knock-Out